OBO ID: GO:0097411
Term Name: hypoxia-inducible factor-1alpha signaling pathway Search Ontology:
Synonyms:
  • HIF1alpha pathway
  • hypoxia-inducible factor signaling
  • hypoxia-inducible factor-1alpha signalling pathway
Definition: A series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia. http://www.sabiosciences.com/pathway.php?sn=HIF1Alpha_Pathway
References:
Ontology: GO: Biological Process   QuickGO   AmiGO
PHENOTYPE No data available