OBO ID: GO:0097342
Term Name: ripoptosome Search Ontology:
Synonyms:
  • necrosome
  • TNFR1 complex II
  • Tnfr1-CII
Definition: A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more. (2)
References:
Ontology: GO: Cellular Component    QuickGO    AmiGO
EXPRESSION No data available
PHENOTYPE No data available