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ZIRC
OBO ID: GO:0086024
Term Name: adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate Search Ontology:
Synonyms:
  • activation of funny current by beta-adrenergic receptor signaling pathway
  • adenylate cyclase-activating cardiac adrenergic receptor signaling pathway
  • adrenergic receptor signaling pathway involved in positive regulation of heart rate
  • adrenergic receptor signalling pathway involved in positive regulation of heart rate
  • beta adrenergic receptor signaling pathway involved in positive regulation of heart rate
  • Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate
  • If activation by beta-adrenergic receptor signaling pathway
Definition: An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of heart contraction. Binding of adrenalin or noradrenalin to a beta-adrenergic receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gs protein. Gs activates adenylate cyclase to increase intracellular cyclic-AMP (cAMP) levels. cAMP binds directly to F-channels to allow an inward flow of sodium (known as funny current, or If current). The funny current is responsible for membrane depolarization and an increase in heart rate.21099118
References:
Ontology: GO: Biological Process   QuickGO   AmiGO
PHENOTYPE No data available