OBO ID: GO:0070371
Term Name: ERK1 and ERK2 cascade Search Ontology:
Synonyms:
  • ERK cascade
  • ERK1 and ERK2 signaling pathway
  • ERK1 and ERK2 signalling pathway
  • ERK1 cascade
  • ERK1/2 cascade
  • ERK2 cascade
  • extracellular signal-regulated kinase 1/2 (ERK1/2) cascade
  • extracellular signal-regulated kinase 1/2 cascade
  • MAPK1 cascade
  • MAPK3 cascade
Definition: An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. (4)
References:
Ontology: GO: Biological Process   QuickGO   AmiGO
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