OBO ID: GO:0070371

Term Name:	ERK1 and ERK2 cascade		Search Ontology:
Synonyms:	ERK cascade ERK1 and ERK2 signaling pathway ERK1 and ERK2 signalling pathway ERK1 cascade ERK1/2 cascade ERK2 cascade extracellular signal-regulated kinase 1/2 (ERK1/2) cascade extracellular signal-regulated kinase 1/2 cascade MAPK1 cascade MAPK3 cascade
Definition:	A MAPK cascade containing at least the ERK1 or ERK2 MAP kinases. It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and of ERK1 or ERK2. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier. The ERK1/ERK2 cascade is activated by mitogens, growth factors, G protein-coupled receptors, and results in cellular responses such as cell proliferation, cell differentiation and development. (3)
References:
Ontology:	GO: Biological Process    QuickGO    AmiGO