OBO ID: GO:0070059
Term Name: intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress Search Ontology:
Synonyms:
  • apoptosis in response to endoplasmic reticulum stress
  • apoptosis in response to ER stress
  • apoptosis triggered by ER stress
  • endoplasmic reticulum stress-induced apoptosis
  • ER stress-induced apoptosis
  • intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress
Definition: A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. 18701708
References:
Ontology: GO: Biological Process   QuickGO   AmiGO
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