OBO ID: GO:0051880
Term Name: G-quadruplex DNA binding Search Ontology:
Synonyms:
  • G quadruplex DNA binding
  • G quartet binding
  • G quartet DNA binding
  • G-DNA binding
  • G-quartet binding
  • G-quartet DNA binding
  • quadruplex DNA binding
  • tetraplex DNA binding
Definition: Interacting selectively and non-covalently with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome. (2)
References:
Ontology: GO: Molecular Function   QuickGO   AmiGO
PHENOTYPE No data available