OBO ID: GO:0043491

Term Name:	phosphatidylinositol 3-kinase/protein kinase B signal transduction		Search Ontology:
Synonyms:	AKT signal transduction AKT signaling AKT signaling cascade AKT signalling cascade phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction PI3K-PKB/Akt pathway PI3K/Akt signal transduction PI3K/PKB signal transduction PKB signal transduction PKB signaling PKB signaling cascade PKB signalling cascade protein kinase B signal transduction protein kinase B signaling protein kinase B signaling cascade protein kinase B signalling cascade
Definition:	An intracellular signaling cassette that starts with phosphatidylinositol 3-kinase (PI3K) activation, production of phosphatidylinositol 3-phosphate (PI3P), activation of PDK1, which recruits and ending with the activation of protein kinase B (PKB, also known as Akt). PI3K is activated by cell surface receptors. Note that PTEN is an inhibitor of the pathway. (2)
References:
Ontology:	GO: Biological Process    QuickGO    AmiGO