OBO ID: GO:0039530

Term Name:	MDA-5 signaling pathway		Search Ontology:
Synonyms:	IFIH1 signaling pathway MDA-5 signalling pathway MDA5 signaling pathway melanoma differentiation-associated gene 5 signaling pathway
Definition:	The series of molecular signals initiated by the binding of dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1). MDA-5 detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines. (2)
References:
Ontology:	GO: Biological Process    QuickGO    AmiGO