OBO ID: GO:0039530
Term Name: MDA-5 signaling pathway Search Ontology:
  • IFIH1 signaling pathway
  • MDA-5 signalling pathway
  • MDA5 signaling pathway
  • melanoma differentiation-associated gene 5 signaling pathway
Definition: Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. MDA-5 detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. 19620789
Ontology: GO: Biological Process   QuickGO   AmiGO
PHENOTYPE No data available