OBO ID: GO:0038014
Term Name: negative regulation of insulin receptor signaling pathway by insulin receptor internalization Search Ontology:
Synonyms:
  • agonist-stimulated insulin receptor internalization
  • negative regulation of insulin receptor signalling pathway by insulin receptor internalization
Definition: Any process in which internalization of an insulin receptor stops, prevents, or reduces the frequency, rate or extent of insulin receptor signal transduction. Internalization of insulin in association with its receptor clears insulin from the circulation and is necessary for subsequent insulin dissociation from the receptor and insulin degradation. (4)
References:
Ontology: GO: Biological Process    QuickGO    AmiGO
PHENOTYPE No data available