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ZIRC
OBO ID: GO:0038005
Term Name: peptide bond cleavage involved in epidermal growth factor receptor ligand maturation Search Ontology:
Synonyms:
  • EGFR ligand maturation by peptide bond cleavage
  • EGFR ligand processing
  • epidermal growth factor receptor ligand processing
  • peptide bond cleavage involved in EGFR ligand maturation
Definition: The hydrolysis of a peptide bond or bonds within a ligand for the epidermal growth factor receptor, as part of protein maturation, the process leading to the attainment of the full functional capacity of a protein. In Drosophila for example, in the Golgi apparatus of the signal producing cell, Spitz is cleaved within its transmembrane domain to release a functional soluble extracellular fragment. (2)
References:
Ontology: GO: Biological Process   QuickGO   AmiGO
PHENOTYPE No data available