OBO ID: GO:0035329

Term Name:	hippo signaling		Search Ontology:
Synonyms:	hippo signal transduction hippo signaling cascade hippo signaling pathway hippo signalling cascade Salvador-Warts-Hippo signaling pathway SWH pathway
Definition:	An intracellular signaling cascade that starts with the activation of hippo (STK4/MST1 and STK3/MST2 in mammals and hpo kinase in Drosophila). Hippo then phosphorylates LATS1/2, which in turn phosphoylates the transcriptional co-activator YAP1 (yki in Drosophila), leading to its cytosolic retention and/or degradation. (3)
References:
Ontology:	GO: Biological Process    QuickGO    AmiGO