| OBO ID: GO:0034098 |
| Term Name: | VCP-NPL4-UFD1 AAA ATPase complex | Search Ontology: | |
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| Definition: | A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry). (2) | ||
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| Ontology: | GO: Cellular Component QuickGO AmiGO |
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EXPRESSION
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PHENOTYPE
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