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midbrain-hindbrain boundary development
isthmic organizer development
isthmomesencephalic boundary development
midbrain-hindbrain orgainizer development
The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.