OBO ID: GO:0016469
Term Name: proton-transporting two-sector ATPase complex Search Ontology:
Synonyms:
  • hydrogen-transporting two-sector ATPase complex
  • vacuolar hydrogen-transporting ATPase
Definition: A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible. (2)
References:
Ontology: GO: Cellular Component    QuickGO    AmiGO
expand   EXPRESSION
PHENOTYPE No data available