ZFIN GO: Biological Process: complement activation

OBO ID: GO:0006956

Term Name:	complement activation		Search Ontology:
Synonyms:	complement activity complement cascade complement response
Definition:	Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. 0781735149
References:
Ontology:	GO: Biological Process QuickGO AmiGO

Relationships

is a type of:	activation of immune response humoral immune response immune effector process activation of immune response humoral immune response immune effector process Show first 5 Terms
has subtype:	activation of membrane attack complex complement activation, alternative pathway complement activation, classical pathway complement activation, lectin pathway activation of membrane attack complex complement activation, alternative pathway complement activation, classical pathway complement activation, lectin pathway Show first 5 Terms
has_part:	protein activation cascade protein activation cascade Show first 5 Terms
inverse has_part:	complement-dependent cytotoxicity complement-dependent cytotoxicity Show first 5 Terms
negatively regulated by:	negative regulation of complement activation negative regulation of complement activation Show first 5 Terms
positively regulated by:	positive regulation of complement activation positive regulation of complement activation Show first 5 Terms
regulated by:	regulation of complement activation regulation of complement activation Show first 5 Terms

PHENOTYPE No data available