OBO ID: GO:0005680
Term Name: anaphase-promoting complex Search Ontology:
Synonyms:
  • anaphase promoting complex
  • APC
  • cyclosome
Definition: A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B. (2)
References:
Ontology: GO: Cellular Component    QuickGO    AmiGO
EXPRESSION No data available
PHENOTYPE No data available