OBO ID: GO:0002169
Term Name: 3-methylcrotonyl-CoA carboxylase complex, mitochondrial Search Ontology:
Synonyms:
  • mitochondrial 3-methylcrotonyl-CoA carboxylase holoenzyme
  • mitochondrial MCCC complex
  • mitochondrial methylcrotonoyl-CoA carboxylase complex
Definition: A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA. (3)
References:
Ontology: GO: Cellular Component    QuickGO    AmiGO
EXPRESSION No data available
PHENOTYPE No data available