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OBO ID: GO:0000176
Term Name: nuclear exosome (RNase complex) Search Ontology:
  • eukaryotic exosome multienzyme ribonuclease complex
  • nuclear exosome (ribonuclease complex)
  • nuclear exosome multienzyme ribonuclease complex
Definition: A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. (3)
Ontology: GO: Cellular Component   QuickGO   AmiGO
EXPRESSION No data available
PHENOTYPE No data available