OBO ID: DOID:0060018 |
Term Name: | CD3gamma deficiency | Search Ontology: | |
---|---|---|---|
Synonyms: |
|
||
Definition: | A severe combined immunodeficiency that has_material_basis_in autosomal recessive mutations in the gene coding for T-cell surface glycoprotein CD3gamma chain precursors. Patients with CD3gamma deficiency have a severe defect in the expression of the T-cell receptor CD3-complex. Affected patients have decreased T-cell numbers and function; B cells are variably affected. https://www.ncbi.nlm.nih.gov/pubmed/16264327 | ||
References: | |||
Ontology: | Human Disease ( DOID:0060018 ) |
OTHER CD3gamma deficiency PAGES
GENES INVOLVED
No data available
ZEBRAFISH MODELS
No data available
PHENOTYPE
No data available
CITATIONS: None
Your Input Welcome
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if
additional information is required.
Oops. Something went wrong. Please try again later.