ZFIN Cell Ontology: early pro-B cell

OBO ID: CL:0002046

Term Name:	early pro-B cell		Search Ontology:
Synonyms:
Definition:	A pro-B cell that is CD22-positive, CD34-positive, CD38-positive and TdT-positive (has TdT activity). Pre-BCR is expressed on the cell surface. Cell is CD19-negative, CD20-negative, complement receptor type 2-negative and CD10-low. D-to-J recombination of the heavy chain occurs at this stage. 18432934
References:
Ontology:	Cell Ontology

Relationships

develops into:	late pro-B cell late pro-B cell Show first 5 Terms
is a type of:	pro-B cell pro-B cell Show first 5 Terms
has_low_plasma_membrane_amount:	neprilysin neprilysin Show first 5 Terms
has_plasma_membrane_part:	ADP-ribosyl cyclase 1 B-cell receptor CD22 CD34 molecule pre-B cell receptor complex ADP-ribosyl cyclase 1 B-cell receptor CD22 CD34 molecule pre-B cell receptor complex Show first 5 Terms
lacks_plasma_membrane_part:	CD19 molecule complement receptor type 2 membrane-spanning 4-domains subfamily A member 1 CD19 molecule complement receptor type 2 membrane-spanning 4-domains subfamily A member 1 Show first 5 Terms
participates_in:	immunoglobulin heavy chain V-D-J recombination immunoglobulin heavy chain V-D-J recombination Show first 5 Terms

PHENOTYPE No data available