OBO ID: CHEBI:94186 |
Term Name: | tubastatin A | Search Ontology: | |
---|---|---|---|
Synonyms: |
|
||
Definition: | A pyridoindole that is 1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indole which is substituted on the tetrahydropyridine nitrogen by a methyl group and on the indole nitrogen by a p-[N-(hydroxy)aminocarbonyl]benzyl group. It is a histone deacetylase 6 (HDAC6) inhibitor that is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold). | ||
References: |
|
||
Ontology: | ChEBI ( EBI ) |
PHENOTYPE
No data available