OBO ID: CHEBI:92211

Term Name:	SL-327		Search Ontology:
Synonyms:	3-amino-3-[(4-aminophenyl)sulfanyl]-2-[2-(trifluoromethyl)phenyl]acrylonitrile 3-amino-3-[(4-aminophenyl)thio]-2-[2-(trifluoromethyl)phenyl]-2-propenenitrile alpha-{amino[(4-aminophenyl)thio]methylene}-2-(trifluoromethyl)benzeneacetonitrile SL 327 SL327
Definition:	A nitrile that is acrylonitrile in which the hydrogen attached to the same carbon as the cyano group has been replaced by an o-(trifluoromethyl)phenyl group, while the remaining hydrogens of the ethenyl group have been replaced by amino and (4-aminophenyl)sulfanyl groups. The configuration of the double bond is not specified. It is an inhibitor of MEK1 and MEK2.
References:	CAS:305350-87-2 LINCS:LSM-2253 PMID:10969080 PMID:12490588 PMID:18766328 PMID:21074569 PMID:21312031 Reaxys:9423720
Ontology:	ChEBI  ( EBI )