ZFIN ChEBI: sertraline

OBO ID: CHEBI:9123

Term Name:	sertraline		Search Ontology:
Synonyms:	(+)-sertraline (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine (1S,4S)-sertraline (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine cis-(+)-sertraline CP 51974 sertralina Sertraline sertralinum
Definition:	A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder.
References:	Beilstein:5753709 CAS:79617-96-2 DrugBank:DB01104 Drug_Central:2436 HMDB:HMDB0005010 KEGG:C07246 KEGG:D02360 LINCS:LSM-3843 PDBeChem:SRE PMID:19502000 PMID:21823671 Patent:US4536518 Reaxys:5753709 Wikipedia:Sertraline
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	dichlorobenzene secondary amino compound tetralins dichlorobenzene secondary amino compound tetralins Show first 5 Terms
has_parent_hydride:	tetralin tetralin Show first 5 Terms
has_role:	antidepressant serotonin uptake inhibitor antidepressant serotonin uptake inhibitor Show first 5 Terms
inverse is_conjugate_acid_of:	sertraline(1+) sertraline(1+) Show first 5 Terms
is_conjugate_base_of:	sertraline(1+) sertraline(1+) Show first 5 Terms

PHENOTYPE No data available