OBO ID: CHEBI:90998

Term Name:	alvocidib hydrochloride		Search Ontology:
Synonyms:	(3S,4R)-4-[2-(2-chlorophenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-3-hydroxy-1-methylpiperidinium chloride 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one hydrochloride alvocidib HCl HL 275 HL-275 HMR 1275 HMR-1275 L 86 8275 L86-8275
Definition:	A hydrochloride salt resulting from the formal reaction of equimolar amounts of alvocidib and hydrogen chloride. A cyclin-dependent kinase 9 (CDK9) inhibitor, it has been studied for the treatment of acute myeloid leukaemia, arthritis and atherosclerotic plaque formation.
References:	CAS:131740-09-5 DrugBank:DB03496 KEGG:D02880 PMID:1279187 PMID:21541623 PMID:21556497 PMID:8002990 PMID:8250970 PMID:9269999 PMID:9815683
Ontology:	ChEBI  ( EBI )