OBO ID: CHEBI:8988
Term Name: SN-38 Search Ontology:
Synonyms:
  • (4S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
  • 10-Hydroxy-7-ethylcamptothecin
  • 7-Ethyl-10-hydroxy-20(S)-camptothecin
  • 7-Ethyl-10-hydroxycamptothecin
  • NK 012
  • NK-012
  • SN 38
  • SN 38 lactone
  • SN-38
Definition: A member of the class of pyranoindolizinoquinolines that is (4S)-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione bearing two additional ethyl substituents at positions 4 and 11 as well as two additional hydroxy substituents at positions 4 and 9. It is the active metabolite of irinotecan and is ~1000 times more active than irinotecan itself.
References:
Ontology: ChEBI  ( EBI )
Relationships
is a type of:
has_role:
inverse has_functional_parent:
PHENOTYPE No data available

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