OBO ID: CHEBI:8455

Term Name:	proguanil		Search Ontology:
Synonyms:	1-(p-chlorophenyl)-5-isopropylbiguanide Chlorguanide Chloroguanide N-(4-Chlorophenyl)-N'-(isopropyl)-imidodicarbonimidic diamide N-(4-chlorophenyl)-N'-(propan-2-yl)imidodicarbonimidic diamide proguanil proguanilum
Definition:	A biguanide compound which has isopropyl and p-chlorophenyl substituents on the terminal N atoms. A prophylactic antimalarial drug, it works by inhibiting the enzyme dihydrofolate reductase, which is involved in the reproduction of the malaria parasites Plasmodium falciparum and P. vivax within the red blood cells.
References:	Beilstein:2811599 CAS:500-92-5 DrugBank:DB01131 Drug_Central:2282 HMDB:HMDB0015263 KEGG:C07631 KEGG:D08428 LINCS:LSM-2618 PMID:10348748 PMID:10848923 PMID:15504827 PMID:8866915 Reaxys:2811599 Wikipedia:Proguanil
Ontology:	Chebi