OBO ID: CHEBI:77788

Term Name:	temafloxacin		Search Ontology:
Synonyms:	(+-)-1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (+-)-temafloxacin A 62254 rac-1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid rac-temafloxacin T 1258 temafloxacin temafloxacine temafloxacino temafloxacinum
Definition:	A racemate comprising equimolar amounts of (R)- and (S)-temafloxacin. Both enantiomers both exhibit similar pharmacological profiles. Temafloxacin was briefly used (either as the free base or as the hydrochloride salt) as an antibacterial drug but was withdrawn worldwide in 1992 following reports of serious side effects, including severe hypoglycaemia, haemolytic anaemia, liver and kidney dysfunction, anaphylaxis, and death.
References:	CAS:108319-06-8 DrugBank:DB01405 PMID:1318680 PMID:1319872 PMID:1662889 PMID:1662893 PMID:1662895 PMID:1666497 PMID:1846917 Patent:EP131839 Patent:US4730000 Reaxys:4301726 Wikipedia:Temafloxacin
Ontology:	ChEBI  ( EBI )