OBO ID: CHEBI:76258

Term Name:	oxyphenbutazone		Search Ontology:
Synonyms:	1-(p-Hydroxyphenyl)-2-phenyl-4-butyl-3,5-pyrazolidinedione 1-Phenyl-2-(p-hydroxyphenyl)-3,5-dioxo-4-butylpyrazolidine 1-Phenyl-2-(p-hydroxyphenyl)-3,5-dioxo-4-n-butylpyrazolidine 3,5-Dioxo-1-phenyl-2-(p-hydroxyphenyl)-4-N-butylpyrazolidene 4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidinedione 4-Butyl-1-(p-hydroxyphenyl)-2-phenyl-3,5-pyrazolidinedione 4-Butyl-2-(4-hydroxyphenyl)-1-phenyl-3,5-dioxopyrazolidine 4-Butyl-2-(p-hydroxyphenyl)-1-phenyl-3,5-pyrazolidinedione Hydroxyphenylbutazon Oxi-fenibutol oxifenbutazona Oxifenylbutazon Oxiphenbutazonum oxyphenbutazone oxyphenbutazonum Oxyphenylbutazone p-Hydroxyphenylbutazone p-Oxyphenylbutazone
Definition:	A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
References:	CAS:129-20-4 DrugBank:DB03585 Drug_Central:2036 KEGG:C19494 KEGG:D08324 LINCS:LSM-5029 PMID:1222682 PMID:141661 PMID:14345781 PMID:18963985 PMID:19161668 PMID:20299217 PMID:21428758 PMID:23012453 PMID:23983013 PMID:2862290 PMID:380595 PMID:501546 PMID:546857 PMID:6617711 PMID:6860567 PMID:6894379 PMID:7001487 PMID:7309664 PMID:7368966 PMID:766157 PMID:835859 Patent:EP642336 Patent:US2008014272 Patent:WO2005107748 Reaxys:307474 Wikipedia:Oxyphenbutazone
Ontology:	ChEBI  ( EBI )