ZFIN ChEBI: amfenac

OBO ID: CHEBI:75915

Term Name:	amfenac		Search Ontology:
Synonyms:	(2-amino-3-benzoylphenyl)acetic acid (2-Amino-3-benzoylphenyl)essigsaeure 2-amino-3-benzoylbenzeneacetic acid amfenac amfenaco amfenacum
Definition:	An oxo monocarboxylic acid that is benzophenone in which one of the phenyl groups is substituted by an amino group and a carboxymethyl group at position 2 and 3, respectively. The corresponding carboxamide, nepafenac, is a prodrug of amfenac and is used for the treatment of pain and inflammation following cataract surgery.
References:	CAS:51579-82-9 Drug_Central:154 KEGG:D07443 PMID:10850857 PMID:19897019 PMID:3540874 PMID:8320556 Patent:DE2324768 Patent:US4045576 Reaxys:2381781 Wikipedia:Amfenac
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	amino acid benzophenones oxo monocarboxylic acid primary amino compound substituted aniline amino acid benzophenones oxo monocarboxylic acid primary amino compound substituted aniline Show first 5 Terms
has_role:	antipyretic cyclooxygenase 1 inhibitor cyclooxygenase 2 inhibitor non-narcotic analgesic non-steroidal anti-inflammatory drug antipyretic cyclooxygenase 1 inhibitor cyclooxygenase 2 inhibitor non-narcotic analgesic non-steroidal anti-inflammatory drug Show first 5 Terms
inverse has_functional_parent:	bromfenac bromfenac Show first 5 Terms
inverse is_conjugate_base_of:	amfenac(1-) amfenac(1-) Show first 5 Terms
is_conjugate_acid_of:	amfenac(1-) amfenac(1-) Show first 5 Terms

PHENOTYPE No data available