ZFIN Chebi: (R,R)-tramadol

OBO ID: CHEBI:75725

Term Name:	(R,R)-tramadol		Search Ontology:
Synonyms:	(+)-tramadol (+)-trans-2-(Dimethylaminomethyl)-1-(m-methoxyphenyl)cyclohexanol (1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
Definition:	A 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol in which both stereocentres have R-configuration; the (R,R)-enantiomer of the racemic opioid analgesic tramadol, it exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer.
References:	CAS:123154-38-1 CAS:27203-92-5 KEGG:C07153 KEGG:D08623 LINCS:LSM-5221 Reaxys:9590387 VSDB:3008 Wikipedia:Tramadol
Ontology:	Chebi

Relationships

is a type of:	2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol Show first 5 Terms
has_role:	adrenergic uptake inhibitor antitussive capsaicin receptor antagonist delta-opioid receptor agonist kappa-opioid receptor agonist ... Show All 13 Terms adrenergic uptake inhibitor antitussive capsaicin receptor antagonist delta-opioid receptor agonist kappa-opioid receptor agonist metabolite mu-opioid receptor agonist muscarinic antagonist nicotinic antagonist NMDA receptor antagonist opioid analgesic serotonergic antagonist serotonin uptake inhibitor Show first 5 Terms
inverse has_part:	tramadol tramadol Show first 5 Terms
inverse is_conjugate_acid_of:	(R,R)-tramadol(1+) (R,R)-tramadol(1+) Show first 5 Terms
inverse is_enantiomer_of:	(S,S)-tramadol (S,S)-tramadol Show first 5 Terms
is_conjugate_base_of:	(R,R)-tramadol(1+) (R,R)-tramadol(1+) Show first 5 Terms
is_enantiomer_of:	(S,S)-tramadol (S,S)-tramadol Show first 5 Terms

PHENOTYPE No data available