OBO ID: CHEBI:746859

Term Name:	travoprost		Search Ontology:
Synonyms:	isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[(alpha,alpha,alpha-trifluoro-m-tolyl)oxy]-1-butenyl}cyclopentyl)-5-heptenoate propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-5-enoate Travatan Travatan Z Travoprost travoprostum
Definition:	The isopropyl ester of prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2alpha, ophthalmic solutions of travoprost are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. It is a pro-drug; the isopropyl ester group is hydrolysed by esterases in the cornea to the biologically active free acid, fluprostenol.
References:	CAS:157283-68-6 DrugBank:DB00287 Drug_Central:2716 HMDB:HMDB0014432 KEGG:D01964 PMID:22050687 PMID:22167541 PMID:22259229 Reaxys:8739060 Wikipedia:Travoprost
Ontology:	ChEBI  ( EBI )