OBO ID: CHEBI:74514 |
Term Name: | 6-aminonicotinamide | Search Ontology: | |
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Definition: | A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 6-aminonicotinic acid with ammonia. An inhibitor of the NADP(+)-dependent enzyme, 6-phosphogluconate dehydrogenase, it interferes with glycolysis, resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, such as cisplatin, in killing cancer cells. | ||
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Ontology: | ChEBI ( EBI ) |
PHENOTYPE
No data available