OBO ID: CHEBI:72297

Term Name:	lomitapide		Search Ontology:
Synonyms:	AEGR 733 AEGR 773 AEGR-773 AEGR733 AEGR773 BMS 201038 BMS201038 Lojuxta lomitapida lomitapide lomitapidum N-(2,2,2-trifluoroethyl)-9-{4-[4-({[4'-(trifluoromethyl)biphenyl-2-yl]carbonyl}amino)piperidin-1-yl]butyl}-9H-fluorene-9-carboxamide
Definition:	A member of the class of benzamides obtained by formal condensation of the carboxy group of 4'-(trifluoromethyl)biphenyl-2-carboxylic acid with the primary amino group of 9-[4-(4-aminopiperidin-1-yl)butyl]-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide. Used (as its mesylate salt) as a complement to a low-fat diet and other lipid-lowering treatments in patients with homozygous familial hypercholesterolemia.
References:	CAS:182431-12-5 DrugBank:DB08827 Drug_Central:4721 KEGG:D09637 PMID:17215532 PMID:20127562 PMID:21846156 PMID:22963620 PMID:23122767 PMID:23122768 PMID:23147576 PMID:24366202 PMID:25257075 PMID:25702706 PMID:26120010 PMID:26686567 PMID:27055957 PMID:27232459 PMID:27785928 PMID:28154305 PMID:28239069 PMID:28255870 PMID:28432645 PMID:28598687 PMID:28716835 Patent:US2003162788 Patent:US2008161279 Patent:US2010273829 Patent:US2011288064 Patent:US2011288110 Patent:US2012035204 Patent:US2012071458 Reaxys:13754976 Wikipedia:Lomitapide
Ontology:	ChEBI  ( EBI )