OBO ID: CHEBI:681848

Term Name:	doxapram		Search Ontology:
Synonyms:	(+-)-doxapram 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone 1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one Doxapram
Definition:	A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
References:	Beilstein:628691 CAS:309-29-5 DrugBank:DB00561 Drug_Central:953 KEGG:D07873 LINCS:LSM-5058 PMID:19663568 PMID:20140700 PMID:25819170 PMID:26896538 PMID:4122029 PMID:4126096 PMID:527638 Patent:BE613734 Patent:US3192206 Reaxys:628691 VSDB:1819 Wikipedia:Doxapram
Ontology:	ChEBI  ( EBI )