OBO ID: CHEBI:67169 |
Term Name: | cortistatins | Search Ontology: | |
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Definition: | Any member of a class of steroidal alkaloids obtained from the marine sponge Corticium simplex, with a basic skeleton that is (5R,8beta)-5,8-epoxy-9,19-cyclo-9,10-secoandrostane, bearing a dimethylamino substituent at position 3 and an isoquinolin-7-yl or isoquinolin-7-yl-derived substituent at position 17. They selectively inhibit proliferation of human umbilical vein endothelial cells (HUVECs). | ||
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Ontology: | ChEBI ( EBI ) |
PHENOTYPE
No data available