OBO ID: CHEBI:64311 |
Term Name: | fosaprepitant dimeglumine | Search Ontology: | |
---|---|---|---|
Synonyms: |
|
||
Definition: | An organoammonium salt obtained by reaction of fosaprepitant with two equivalents of 1-deoxy-1-(methylamino)-D-glucitol. A substance P/neurokinin 1 (NK1) receptor antagonist. Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. Aprepitant has little or no affinity for serotonin (5-HT3), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting and postoperative nausea and vomiting | ||
References: |
|
||
Ontology: | ChEBI ( EBI ) |
PHENOTYPE
No data available