OBO ID: CHEBI:64207

Term Name:	spiramide		Search Ontology:
Synonyms:	8-[3-(4-fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one AMI-193 espiramida spiramide spiramidum
Definition:	An azaspiro compound that consists of 1,3,8-triazaspiro[4.5]decan-4-one having a phenyl group attached to N-1 and a 3-(4-fluorophenoxy)propyl attached to N-8. Selective 5-HT antagonist, which binds to 5-HT2 sites as potently as spiperone but has lower affinity for 5-HT2C receptors. Also a high affinity D2 receptor antagonist (Ki = 3 nM). Lacks the disruptive effect of spiperone on animal behaviour.
References:	CAS:510-74-7 LINCS:LSM-4124 PMID:11124389 PMID:17965538 PMID:19875674 PMID:4474849 PMID:4776656 Patent:US3238216 Reaxys:631679 Wikipedia:Spiramide
Ontology:	ChEBI  ( EBI )