OBO ID: CHEBI:64159
Term Name: 2-methyl-6-(phenylethynyl)pyridine Search Ontology:
Synonyms:
  • 2-methyl-6-(phenylethynyl)pyridine
  • 6-Methyl-2-(phenylethynyl)pyridine
  • MPEP
Definition: A methylpyridine that coinsists of 2-methylp[yridine bearing an additional phenylethynyl group at position 6. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.
References:
Ontology: ChEBI  ( EBI )
Relationships
is a type of:
has_parent_hydride:
has_role:
inverse is_conjugate_acid_of:
is_conjugate_base_of:
PHENOTYPE No data available

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