ZFIN ChEBI: CGP 78608 hydrochloride

OBO ID: CHEBI:64065

Term Name:	CGP 78608 hydrochloride		Search Ontology:
Synonyms:	(1S)-N-[(7-bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl]-1-phosphonoethanaminium chloride [(1S)-1-{[(7-bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl]amino}ethyl]phosphonic acid hydrochloride
Definition:	A hydrochloride that is the monohydrochloride salt of CGP 78608. Potent and selective NMDA antagonist that acts through the glycine site (IC50 = 5 nM). Displays >500-fold selectivity over kainate and AMPA receptors (IC50 values are 2.7 and 3 muM respectively). Anticonvulsant in vivo following systemic administration.
References:
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	hydrochloride hydrochloride Show first 5 Terms
has_role:	anticonvulsant NMDA receptor antagonist prodrug anticonvulsant NMDA receptor antagonist prodrug Show first 5 Terms
inverse is_conjugate_acid_of:	CGP 78608(1+) CGP 78608(1+) Show first 5 Terms
is_conjugate_base_of:	CGP 78608(1+) CGP 78608(1+) Show first 5 Terms

PHENOTYPE No data available