| Term Name: |
7-chlorokynurenic acid |
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Search Ontology:
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| Synonyms: |
- 7-chloro-4-hydroxy-2-carboxyquinoline
- 7-chloro-4-hydroxyquinoline-2-carboxylic acid
- 7-CKA
- 7-Cl-KYNA
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| Definition: |
A quinolinemonocarboxylic acid that is quinaldic acid which is substituted by a hydroxy group at position 4 and by a chlorine at position 7. It is a potent NMDA glutamate receptor antagonist which antagonizes the strychnine-insensitive glycine site of the NMDA receptor. It also prevents neurodegeneration produced by quinolinic acid.
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| References: |
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| Ontology: |
Chebi
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