ZFIN ChEBI: tenofovir (anhydrous)

OBO ID: CHEBI:63625

Term Name:	tenofovir (anhydrous)		Search Ontology:
Synonyms:	(R)-PMPA ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid anh. tenofovir anhydrous tenofovir tenofovir tenofovir (anh.)
Definition:	A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection.
References:	CAS:147127-20-6 DrugBank:DB00300 HMDB:HMDB0014445 KEGG:D06074 LINCS:LSM-5340 PMID:11777298 PMID:25017682 PMID:28166217 PMID:28503983 Reaxys:7415378 Wikipedia:Tenofovir
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	nucleoside analogue phosphonic acids nucleoside analogue phosphonic acids Show first 5 Terms
has_role:	antiviral drug drug metabolite HIV-1 reverse transcriptase inhibitor antiviral drug drug metabolite HIV-1 reverse transcriptase inhibitor Show first 5 Terms
inverse has_functional_parent:	tenofovir disoproxil tenofovir disoproxil Show first 5 Terms
inverse has_part:	tenofovir hydrate tenofovir hydrate Show first 5 Terms
inverse is_conjugate_base_of:	tenofovir(1-) tenofovir(1-) Show first 5 Terms
is_conjugate_acid_of:	tenofovir(1-) tenofovir(1-) Show first 5 Terms

PHENOTYPE No data available