OBO ID: CHEBI:63610

Term Name:	misoprostol		Search Ontology:
Synonyms:	(+-)-methyl (1R,2R,3R)-3-hydroxy-2-((E)-(4RS)-4-hydroxy-4-methyl-1-octenyl)-5-oxocyclopentaneheptanoate (11-alpha,13E)-(+-)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester Arthrotec Cytotec Methyl (+-)-11-alpha,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate misoprostol misoprostolum
Definition:	A diastereoisomeric mixture composed of approximately equal amounts of a double racemate of four of the sixteen possible diastereoisomers of methyl (13E)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate that is racemic prostaglandin E1 which is lacking the hydroxy group at position 15, but which has an additional hydroxy group at position 16. It is a synthetic prostaglandin E1 analogue, used in the treatment of gastric and duodenal ulcers. A weak abortifacient, it is also used for cervical ripening prior to surgical termination of pregnancy. The (11R,16S)-diastereoisomer is the pharmacologically active form.
References:	CAS:59122-46-2 DrugBank:DB00929 KEGG:D00419 PMID:10945193 PMID:10949752 PMID:11136959 PMID:1417145 PMID:18690850 PMID:19740175 PMID:2109814 PMID:3080288 Patent:BE827127 Patent:US3965143 Reaxys:4155643 Wikipedia:Misoprostol
Ontology:	ChEBI  ( EBI )