OBO ID: CHEBI:59173

Term Name:	bivalirudin		Search Ontology:
Synonyms:	(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-4-amino-2-[[2-[[2-[[2-[[2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2R)-2-amino-3-cyclohexylpropanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]pyrrolidi bivalirudin bivalirudina bivalirudine bivalirudinum D-phenylalanyl-L-prolyl-L-arginyl-L-prolylglycylglycylglycylglycyl-L-asparaginylglycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-L-leucine
Definition:	A synthetic peptide of 20 amino acids, comprising D-Phe, Pro, Arg, Pro, Gly, Gly, Gly, Gly, Asn, Gly, Asp, Phe, Glu, Glu, Ile, Pro, Glu, Glu, Tyr, and Leu in sequence. A congener of hirudin (a naturally occurring drug found in the saliva of the medicinal leech), it a specific and reversible inhibitor of thrombin, and is used as an anticoagulant.
References:	Beilstein:12004535 CAS:128270-60-0 DrugBank:DB00006 Drug_Central:385 PMID:28844201 PMID:29086730 PMID:29276283 PMID:29342377 PMID:29345439 PMID:29345440 PMID:29345441 PMID:29345444 PMID:29350380 PMID:29377655 PMID:29461391 PMID:29477790 PMID:29544607 PMID:29563377 PMID:29600024 Patent:WO9102750
Ontology:	ChEBI  ( EBI )