OBO ID: CHEBI:582124
Term Name: myriocin Search Ontology:
Synonyms:
  • (2S,3R,4R)-(E)-2-amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic acid
  • (2S,3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid
  • (2S,3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid
  • antibiotic ISP-1
  • antibiotic ISP-I
  • ISP-1
  • ISP-I
  • thermozymocidin
Definition: An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity.
References:
Ontology: ChEBI  ( EBI )
PHENOTYPE No data available