OBO ID: CHEBI:5555

Term Name:	guanadrel		Search Ontology:
Synonyms:	1-(1,4-dioxaspiro[4.5]dec-2-ylmethyl)guanidine guanadrel guanadrelum
Definition:	A spiroketal resulting from the formal condensation of the keto group of cyclohexanone with the hydroxy groups of 1-(2,3-dihydroxypropyl)guanidine. A postganglionic adrenergic blocking agent formerly used (generally as the sulfate salt) for the management of hypertension, it has been largely superseded by other drugs less likely to cause orthostatic hypotension (dizzy spells on standing up or stretching).
References:	Beilstein:8325419 CAS:40580-59-4 DrugBank:DB00226 Drug_Central:1339 HMDB:HMDB0014371 KEGG:C07035 KEGG:D08029 PMID:3896742 PMID:6621504 PMID:7206175 Patent:US3547951 Reaxys:8325419 Wikipedia:Guanadrel
Ontology:	ChEBI  ( EBI )