ZFIN ChEBI: esomeprazole

OBO ID: CHEBI:50275

Term Name:	esomeprazole		Search Ontology:
Synonyms:	(-)-omeprazole (S)-(-)-omeprazole (S)-omeprazole 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Alenia Escz Esofag esomeprazol esomeprazole esomeprazolum Inexium paranova
Definition:	A 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole that has S configuration at the sulfur atom. An inhibitor of gastric acid secretion, it is used (generally as its sodium or magnesium salt) for the treatment of gastro-oesophageal reflux disease, dyspepsia, peptic ulcer disease, and Zollinger-Ellison syndrome.
References:	CAS:119141-88-7 DrugBank:DB00736 Drug_Central:1055 HMDB:HMDB0005009 HMDB:HMDB0014874 KEGG:D07917 PMID:10983736 PMID:15080761 PMID:18407713 PMID:18472988 PMID:23677700 Reaxys:12060639 Wikipedia:Esomeprazole
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Show first 5 Terms
has_role:	anti-ulcer drug EC 1.4.3.4 (monoamine oxidase) inhibitor EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor histamine antagonist anti-ulcer drug EC 1.4.3.4 (monoamine oxidase) inhibitor EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor histamine antagonist Show first 5 Terms
inverse has_part:	omeprazole omeprazole Show first 5 Terms
inverse is_conjugate_base_of:	esomeprazole(1-) esomeprazole(1-) Show first 5 Terms
inverse is_enantiomer_of:	(R)-omeprazole (R)-omeprazole Show first 5 Terms
is_conjugate_acid_of:	esomeprazole(1-) esomeprazole(1-) Show first 5 Terms
is_enantiomer_of:	(R)-omeprazole (R)-omeprazole Show first 5 Terms

PHENOTYPE No data available