OBO ID: CHEBI:50268
Term Name: GABA modulator Search Ontology:
Synonyms:
  • GABA modulators
Definition: A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
References:
Ontology: ChEBI  ( EBI )
PHENOTYPE No data available