OBO ID: CHEBI:4822

Term Name:	ergometrine		Search Ontology:
Synonyms:	(6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid ((S)-2-hydroxy-1-methyl-ethyl)-amide 9,10-didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergoline-8beta(S)-carboxamide 9,10-didehydro-N-(alpha-(hydroxymethyl)ethyl)-6-methylergoline-8-beta-carboxamide [8beta(S)]-9,10-didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergoline-8-carboxamide D-lysergic acid 1-hydroxymethylethylamide D-lysergic acid-L-propanolamide ergobasine ergometrina Ergometrine ergometrinum Ergonovine ergotocine margonovine N-(2-Hydroxy-1-methylethyl)-D-(+)-lysergamide N-(alpha-(hydroxymethyl)ethyl)-D-lysergamide N-[(2S)-1-hydroxypropan-2-yl]-6-methyl-9,10-didehydroergoline-8beta-carboxamide
Definition:	A monocarboxylic acid amide that is lysergamide in which one of the hydrogens attached to the amide nitrogen is substituted by a 1-hydroxypropan-2-yl group (S-configuration). An ergot alkaloid that has a particularly powerful action on the uterus, its maleate (and formerly tartrate) salt is used in the active management of the third stage of labour, and to prevent or treat postpartum of postabortal haemorrhage caused by uterine atony: by maintaining uterine contraction and tone, blood vessels in the uterine wall are compressed and blood flow reduced.
References:	Beilstein:94902 CAS:60-79-7 DrugBank:DB01253 Drug_Central:1042 KEGG:C07543 KEGG:D07905 KNApSAcK:C00001722 MetaCyc:CPD-14457 PMID:15038775 PMID:16147681 PMID:18326144 PMID:2195299 PMID:24173606 PMID:24365208 PMID:25036782 PMID:25252517 PMID:25347567 PMID:6457611 PMID:7190615 PMID:887503 Patent:US2736728 Patent:US2809920 Patent:US3141887 Reaxys:94902 Wikipedia:Ergometrine
Ontology:	ChEBI  ( EBI )