ZFIN ChEBI: clomipramine

OBO ID: CHEBI:47780

Term Name:	clomipramine		Search Ontology:
Synonyms:	3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE 3-chloroimipramine chlorimipramine Clomipramine G 34586 monochlorimipramine
Definition:	A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
References:	Beilstein:1323477 CAS:303-49-1 DrugBank:DB01242 Drug_Central:701 KEGG:C06918 KEGG:D07727 LINCS:LSM-3171 PDBeChem:CXX PMID:12007764 PMID:12084414 PMID:16085036 PMID:17471183 PMID:19747949 PMID:19810911 Patent:CH371799 Patent:US3467650 Reaxys:1323477 Wikipedia:Clomipramine
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	dibenzoazepine dibenzoazepine Show first 5 Terms
has_functional_parent:	imipramine imipramine Show first 5 Terms
has_role:	anticoronaviral agent antidepressant EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor serotonergic antagonist serotonergic drug ... Show All 6 Terms anticoronaviral agent antidepressant EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor serotonergic antagonist serotonergic drug serotonin uptake inhibitor Show first 5 Terms
inverse is_conjugate_acid_of:	clomipramine(1+) clomipramine(1+) Show first 5 Terms
is_conjugate_base_of:	clomipramine(1+) clomipramine(1+) Show first 5 Terms

PHENOTYPE No data available