| Term Name: |
edrophonium chloride |
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Search Ontology:
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| Synonyms: |
- (3-hydroxyphenyl)dimethylethylammonium chloride
- 3-hydroxy-N,N-dimethyl-N-ethylanilinium chloride
- chlorure d'edrophonium
- cloruro de edrofonio
- edrophonii chloridum
- edrophonium chloride
- ethyl(m-hydroxyphenyl)dimethylammonium chloride
- N-ethyl-3-hydroxy-N,N-dimethylanilinium chloride
- N-ethyl-3-hydroxy-N,N-dimethylbenzenaminium chloride
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| Definition: |
The chloride salt of edrophonium. A reversible inhibitor of cholinesterase with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes), it is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
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| References: |
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| Ontology: |
ChEBI
(
EBI
)
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